HPLC seals

As a distributor of HPLC seals, we focus on providing you with both high quality HPLC spare partsand high quality accessories for your laboratory. The spare parts we offer in our online store have been subjected to a variety of tests to ensure that they can actually withstand your requirements in modern chromatography.

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We offer suitable HPLC seals for the models of various manufacturers. Among them are

  • Knauer
  • Agilent
  • Bischoff
  • Piston Seal
  • Beckman
  • Sycam
  • Perkin-Elmer
  • Waters
  • and other manufacturers!

Seals from WICOM

Seals are either made of pure or modified PTFE or, for use in aqueous media, of polyethylene.
The function of a seal in the HPLC pump is to provide a seal between the piston and the pump head: the piston slides back and forth through the inner sealing lip. The movement builds up pressure, with the inner sealing lip pressing against the piston and the outer sealing lip pressing against the inner wall of the pump head.
If the seal closes due to abrasion, the pressure effect decreases and the pump starts to leak. As leakage increases, so does the pressure fluctuation or pulsation of the pump.


Pressure fluctuation as well as pulsation are particularly important in the HPLC area and should only have a small tolerance range. Therefore, it is absolutely essential that the pressure effect is always high and the seal is always tight. At the latest, when these requirements can no longer be met, the seal should be replaced. At this opportunity, it is best to also check the piston for signs of wear, as it may be that this has been affected by the decreasing function of the seal and must also be replaced.
Of course, it is better not to let any leakage occur in the first place, to check all parts regularly and replace them preventively if necessary.


Our offer for you covers different types of products made of and for different materials. You will find in our online store, for example, piston seals (also secondary piston seals), Teflon seals as well as black, gray and white seals.
you will find what you are looking for if you are looking for the following products:

  • Piston seal (primary, secondary)
  • Teflon seal
  • Universal piston seal
  • Support ring
  • Gasket set
  • White, black and gray piston seal
  • Aqua seal
  • High temperature gasket
  • Primary and Secondary Flange Gasket

Before purchasing a product, please note the compatibility with the manufacturer model you are using. Log in to view the prices for the different products.


All of our gaskets are produced exactly for the specific pump. You can see for each product for which device of which manufacturer the seal was produced. If it concerns model series, you will find the reference to the version also with the respective product. All HPLC seals produced by us meet or exceed the specifications given by the instrument manufacturers. This means that you can be sure that there will be no differences in quality after the replacement part has been installed.
We supply suitable seals for pumps from Agilent, Waters, Thermo, Shimadzu, Knauer, Beckman, Dionex, Merck-Hitachi, Jasco and many others.
You can't find the right HPLC seal for your purpose in our online store? Please contact us and tell us the model you are using, we will be happy to find the right spare part for your system!

Contact - Partner for Laboratory Analytics

Modern analytical chromatography is a broad field - and the search for the right spare part is not always easy due to the wide range of products. We are happy to support you in finding the right spare part and suitable HPLC accessories. And not only for seals! We will also be happy to advise you if you need HPLC columns, HPLC valves, HPLC pumps or HPLC detectors, for example. Please do not hesitate to contact us!

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